# The ctDNA revolution: Insights on cancer care: A narrative review

**Authors:** Krutika Mahendra Gohil, Jyothika Venkataswamy Reddy, Saniya Kifayetulla Mulla, Rutu Snehal Shah, Shrunga Kandhi Raghavendra, Rishika Singh, Sagar Mahendra Gohil

PMC · DOI: 10.6026/9732063002001287 · Bioinformation · 2024-10-31

## TL;DR

This paper reviews how circulating tumor DNA (ctDNA) is transforming cancer care by enabling non-invasive detection and monitoring of tumors.

## Contribution

The paper provides a narrative review of ctDNA's role in precision cancer management and evolving genomic tools.

## Key findings

- ctDNA offers a minimally invasive way to analyze tumor DNA in the bloodstream.
- ctDNA is useful for tracking residual disease, relapse, and guiding therapeutic strategies.
- It enhances the precision of tumor monitoring and treatment personalization.

## Abstract

Circulating tumor DNA (ctDNA) is a revolutionary tool in the detection and monitoring of cancer: a minimally invasive, highly
sensitive approach to analysing tumor-specific DNA in the bloodstream. Therefore, it is of interest to explore the current and evolving
landscape of cancer genomics as precision tools in quantifying tumor dynamics. Thus, the role of ctDNA in tracking minimum residual
disease, relapse, recurrence and the tailoring of therapeutic strategies for effective management of tumours is reviewed.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** cancer (MESH:D009369)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11904137/full.md

## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC11904137/full.md

---
Source: https://tomesphere.com/paper/PMC11904137