# Cover Picture

PMC · DOI: 10.1002/ame2.12426 · Animal Models and Experimental Medicine · 2025-03-12

## TL;DR

This paper presents a cover image representing a study on medulloblastoma using patient-derived xenografts and highlights the role of laboratory mice in medical research.

## Contribution

The study uses single-cell transcriptomic sequencing to analyze a patient-derived xenograft model of medulloblastoma.

## Key findings

- The research identifies subcutaneous patient-derived xenografts that recapitulate medulloblastoma.
- The cover image symbolizes children's gratitude for the role of laboratory mice in disease research.

## Abstract

This cover image is based on the article “Single‐cell transcriptomic sequencing identifies subcutaneous patient‐derived xenograft recapitulated medulloblastoma” (https://doi.org/10.1002/ame2.12399) reported by Jiayu Gao, Yahui Zhao, Ziwei Wang, Fei Liu, Xuan Chen, Jialin Mo, Yifei Jiang, Yongqiang Liu, Peiyi Tian, Yanong Li, Kaiwen Deng, Xueling Qi, Dongming Han, Zijia Liu, Zhengtao Yang, Yixi Chen, Yujie Tang, Chunde Li, Hailong Liu, Jiankang Li, Tao Jiang. The image mainly conveys children's gratitude for the contributions made by laboratory mice to disease research and drug screening.

## Linked entities

- **Diseases:** medulloblastoma (MONDO:0002794)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11904089/full.md

---
Source: https://tomesphere.com/paper/PMC11904089