# Clarity Amidst the Smoke: Moyamoya Disease, a Diagnosis Not to Be Missed

**Authors:** Sharifa Alnaqeeb, Diana Kheder, Noor A Abotaiban

PMC · DOI: 10.7759/cureus.78810 · 2025-02-10

## TL;DR

This paper presents a case of moyamoya disease in a 33-year-old woman, highlighting the importance of early diagnosis and surgical treatment.

## Contribution

The novelty lies in the detailed clinical presentation and neuroimaging findings of moyamoya disease in a young adult from the Philippines.

## Key findings

- The patient exhibited acute hemiparesis and a history of TIAs, consistent with moyamoya disease.
- Neuroimaging confirmed ICA, MCA, and ACA occlusion with collateral vessel formation.
- The patient was successfully referred for surgical revascularization.

## Abstract

Moyamoya disease (MMD) is a rare, progressive cerebrovascular disorder characterized by the bilateral stenosis of the internal carotid artery (ICA) and its proximal vessels, leading to the formation of compensatory smoke-like collateral vessels. This report describes the case of a 33-year-old Philippine woman who presented with acute right-sided hemiparesis and had a history of recurrent transient ischemic attacks (TIAs) with similar symptoms. Neuroimaging revealed intracranial hemorrhage and characteristic bilateral occlusion of the internal carotid artery (ICA), middle cerebral artery (MCA), and anterior cerebral artery (ACA) with collateral vessel formation, indicative of moyamoya disease. The patient was referred for surgical revascularization.

## Linked entities

- **Diseases:** Moyamoya disease (MONDO:0016820), transient ischemic attacks (MONDO:0005264)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** occlusion of the internal carotid artery (MESH:D002340), MMD (MESH:D009072), TIAs (MESH:D002546), stenosis of the internal carotid artery (MESH:D016893), cerebrovascular disorder (MESH:D002561), intracranial hemorrhage (MESH:D020300), Smoke (MESH:D015208), hemiparesis (MESH:D010291)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11902914/full.md

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Source: https://tomesphere.com/paper/PMC11902914