# Twist of Fate: Diagnosing and Managing Gallbladder Volvulus in an Elderly Patient

**Authors:** Ali Wuheb, Mohamed Ismaiel, Hassan Abdulrahman, Parth Gada, Ayesha Ragavoodoo, Mehvish Alavi, Prem Thambi

PMC · DOI: 10.7759/cureus.78813 · Cureus · 2025-02-10

## TL;DR

This paper presents a rare case of gallbladder volvulus in an elderly woman, emphasizing the challenges in diagnosis and the importance of timely surgical treatment.

## Contribution

The paper highlights the diagnostic challenges and management of gallbladder volvulus in a high-risk elderly patient with a complex medical history.

## Key findings

- CT scan findings such as the 'swirl sign' and midline gallbladder position aided in the preoperative diagnosis of gallbladder volvulus.
- Urgent laparoscopic cholecystectomy successfully treated the patient with no postoperative complications.
- The case underscores the need for a high index of suspicion in elderly, frail patients with risk factors for gallbladder volvulus.

## Abstract

Gallbladder volvulus (GV) is a rare surgical emergency characterized by the twisting of the gallbladder around its mesentery, leading to vascular compromise and gangrene. It is often misdiagnosed as acute gangrenous cholecystitis due to overlapping symptoms, making preoperative diagnosis challenging. Definitive identification is typically made intraoperatively. Contributory factors include advanced age, female gender, low body mass index, and increased gallbladder mobility. Urgent surgical intervention is crucial to prevent severe complications such as perforation and biliary peritonitis. We report a case of an elderly woman with a low BMI who had a history of right hemicolectomy for locally advanced cecal cancer and ongoing immunotherapy for pelvic recurrence. She presented with acute epigastric pain, nausea, and vomiting but no fever or jaundice. Examination revealed a tender upper abdomen with a palpable mass. Laboratory investigations showed leucocytosis with unremarkable CRP, liver, and renal function tests. A CT scan demonstrated a grossly distended midline gallbladder with a swirl sign at the cystic pedicle, consistent with GV. Supportive management was given, followed by urgent laparoscopic cholecystectomy. Intraoperatively, a gangrenous gallbladder twisted 360° twice around its mesentery was identified and safely removed without complications. The patient made an uneventful recovery and was discharged within 48 hours. This case underscores the diagnostic challenges of GV and highlights the importance of a high index of suspicion, particularly in elderly, frail patients with risk factors. Imaging findings such as the "swirl sign" and midline crossing of the gallbladder on CT scan aid preoperative diagnosis. Urgent surgical intervention remains the cornerstone of management, as delayed treatment can result in significant morbidity.

## Linked entities

- **Diseases:** cecal cancer (MONDO:0006029)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** jaundice (MESH:D007565), fever (MESH:D005334), acute gangrenous cholecystitis (MESH:D041881), cecal cancer (MESH:D002430), epigastric pain (MESH:D010146), GV (MESH:D045822), nausea (MESH:D009325), vomiting (MESH:D014839), gangrene (MESH:D005734), biliary peritonitis (MESH:D010538)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11900904/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11900904/full.md

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Source: https://tomesphere.com/paper/PMC11900904