# Limb Salvage in Patients with Concomitant Advanced Malignancy

**Authors:** Jolyn Hui Qing Pang, Nick Zhi Peng Ng

PMC · DOI: 10.3390/jcm14051642 · Journal of Clinical Medicine · 2025-02-28

## TL;DR

This paper discusses a new approach to treating patients with both advanced cancer and severe leg blood flow issues to improve their quality of life.

## Contribution

The paper proposes a holistic treatment algorithm for patients with advanced malignancy and chronic limb-threatening ischemia.

## Key findings

- A shift in treatment mindset is suggested for patients with advanced malignancy and limb-threatening ischemia.
- A proposed algorithm aims to guide management of these complex cases.
- The approach is intended to improve patient quality of life.

## Abstract

Background: We are experiencing an increasing number of patients presenting with advanced malignancy who are also presenting with chronic limb threatening ischemia. Method: With advancements in medicine and surgery, we are suggesting a shift in mindset of how we treat this group of patients and proposing a more holistic approach for treatment options. Result: In this original article, we highlight our approach in managing such patients and suggest an algorithm. Conclusions: We hope that our article brings awareness and assists vascular surgeons in managing such cases, resulting in improved quality of life for these patients.

## Full-text entities

- **Diseases:** ischemia (MESH:D007511), Malignancy (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11900209/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11900209/full.md

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Source: https://tomesphere.com/paper/PMC11900209