# Influence of Lactobionic Acid on Hydration and Elasticity Parameters in Women Aged 30–40 and 50–60 Years in Comparison to Mandelic Acid

**Authors:** Marlena Warowna, Agnieszka Strzelecka, Beata Kręcisz

PMC · DOI: 10.3390/jcm14051619 · Journal of Clinical Medicine · 2025-02-27

## TL;DR

This study compares how lactobionic and mandelic acids affect skin hydration and elasticity in women aged 30–40 and 50–60.

## Contribution

The study provides age-specific insights into the effectiveness of lactobionic and mandelic acids for skin hydration and elasticity.

## Key findings

- Lactobionic acid improved hydration and elasticity in both age groups.
- Mandelic acid improved elasticity but not hydration in older women.
- Moisturizer enhanced hydration and elasticity in both age groups.

## Abstract

Background/Objectives: Mandelic acid as a chemical peel has been used in cosmetology for years and is being gradually exchanged for lactobionic acid. However, in the cosmetology literature, there is no information on the effectiveness of the aforementioned peels in terms of hydration and elasticity for women’s facial skin depending on their age. The effects of lactobionic and mandelic acid on the skin of women aged 30–40 and 50–60 years are assessed in terms of their moisturizing and elasticizing effects. Methods: The participants of this study were 180 women aged 30–40 and 50–60 years. The selection of the group was random. Contraindications to the examination were excluded in all participants. The level of hydration was assessed using Tewameter and the level of elasticity using a cutometric probe (Courage-Khazaka Multi Test Skin Center MC 1000, Kőln, Germany). The participants also used a moisturizer. Moreover, a series of five exfoliating treatments using 40% mandelic acid or 40% lactobionic acid were performed in 120 of the participants. After 14 days since the last treatment, the assessment of their facial skin’s hydration and elasticity was performed yet again. Results: In the case of women aged 30–40 years, the level of hydration and elasticity increased after using lactobionic and mandelic acid, as well as a moisturizer. In the group of older women aged 50–60 years, the level of elasticity increased after using both acids and moisturizer, but the hydration parameter increased only after the usage of lactobionic acid and moisturizer. Conclusions: In terms of age, lactobionic acid will be more suitable for people aged 50–60, while for women aged 30–40, lactobionic or mandelic acid can be used.

## Linked entities

- **Chemicals:** lactobionic acid (PubChem CID 7314), mandelic acid (PubChem CID 1292)

## Full-text entities

- **Chemicals:** lactobionic (-), Mandelic Acid (MESH:C037938), Lactobionic Acid (MESH:C005608)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC11900206/full.md

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Source: https://tomesphere.com/paper/PMC11900206