# Acute Respiratory Distress Syndrome Following Minimally Invasive Cardiac Surgery

**Authors:** Takashi Nagase, Noriyuki Kashiyama, Masahiro Ryugo, Osamu Monta, Shinichiro Oda

PMC · DOI: 10.7759/cureus.78793 · 2025-02-09

## TL;DR

A 77-year-old woman developed ARDS after minimally invasive heart surgery and recovered with timely treatment.

## Contribution

This case highlights the rare occurrence of ARDS following minimally invasive cardiac surgery.

## Key findings

- ARDS was diagnosed after ruling out other causes of respiratory failure.
- The patient improved with treatment including nitric oxide, methylprednisolone, and Sivelestat.
- Early diagnosis and intervention led to successful recovery and re-extubation.

## Abstract

Acute respiratory distress syndrome (ARDS) incidence following minimally invasive cardiac surgery (MICS) is rare. We report a case of acute respiratory failure following cardiac surgery that was diagnosed as ARDS. A 77-year-old female patient diagnosed with aortic valve stenosis underwent aortic valve replacement via a right thoracotomy. The surgery was uneventful, and the patient was extubated on the day of surgery. However, oxygen saturation steadily declined one day postoperatively, and the patient was re-intubated. Chest radiography revealed bilateral heterogeneous infiltrates. After excluding other differential diagnoses, we diagnosed ARDS based on established diagnostic criteria. Inhalation of nitric oxide, methylprednisolone, and Sivelestat were initiated. The patient’s respiratory status gradually improved, and she was re-extubated eight days postoperatively. She remained stable in the general ward and was transferred for rehabilitation. Early diagnosis and intervention are key for favorable outcomes in these cases.

## Linked entities

- **Chemicals:** nitric oxide (PubChem CID 145068), methylprednisolone (PubChem CID 6741), Sivelestat (PubChem CID 107706)
- **Diseases:** aortic valve stenosis (MONDO:0042981), acute respiratory distress syndrome (MONDO:0006502), ARDS (MONDO:0006502)

## Full-text entities

- **Diseases:** ARDS (MESH:D012128), aortic valve stenosis (MESH:D001024), acute respiratory failure (MESH:D012131)
- **Chemicals:** oxygen (MESH:D010100), methylprednisolone (MESH:D008775), nitric oxide (MESH:D009569), Sivelestat (MESH:C069195)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11897684/full.md

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Source: https://tomesphere.com/paper/PMC11897684