# A Breathtaking Case of Chemotherapy-Induced Pneumonitis

## TL;DR

A rare case of lung inflammation caused by chemotherapy with etoposide is reported in a patient with metastatic seminoma.

## Contribution

This case highlights the under-recognized risk of pneumonitis from etoposide in cancer treatment.

## Key findings

- Etoposide can cause acute pneumonitis in patients receiving chemotherapy.
- Diagnosis of chemotherapy-induced lung toxicity is critical for timely management.
- Pneumonitis occurred after a short IV course of etoposide in a metastatic seminoma patient.

## Abstract

Medication-induced pulmonary toxicity is a rare adverse event that may occur with many chemotherapeutic agents, including etoposide. This agent has been found to cause various toxicities, including anaphylaxis, angioedema, hypotension, and pneumonitis. Etoposide is used in chemotherapy regimens for multiple cancers, including germ-cell tumors. Proper diagnosis of chemotherapy-induced pulmonary toxicity is imperative and should be considered in patients who develop acute respiratory failure during or after chemotherapy. Here, we discuss an unexpected case of etoposide-induced pneumonitis after a short course of IV etoposide in a patient with metastatic seminoma.