# Complete genome sequencing and probiotic trait analysis of Lacticaseibacillus rhamnosus LR110, a human stool isolate from the NORDBIOTIC collection

**Authors:** A. Szczepankowska, B. Cukrowska, T. Aleksandrzak-Piekarczyk

PMC · DOI: 10.1128/mra.01116-24 · Microbiology Resource Announcements · 2025-02-24

## TL;DR

This paper reports the full genome sequence of a probiotic bacteria strain from human stool and identifies genes linked to its potential health benefits.

## Contribution

The study provides a complete genome sequence and identifies probiotic-related genes in Lacticaseibacillus rhamnosus LR110.

## Key findings

- The genome of Lacticaseibacillus rhamnosus LR110 is 2,867,184 base pairs with 46.8% GC content.
- Genes related to thiamine salvage, lactose metabolism, and putrescine biosynthesis were identified.
- These genes suggest potential probiotic properties of the strain.

## Abstract

We present the complete genome of Lacticaseibacillus rhamnosus strain LR110, a human stool isolate from the NORDBIOTIC strain collection. The genome consists of a 2,867,184-bp chromosome with 46.8% GC content. Genomic analysis revealed genes related to thiamine salvage, lactose metabolism, and putrescine biosynthesis, providing insight into the strain’s potential probiotic properties.

## Linked entities

- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Chemicals:** putrescine (MESH:D011700), thiamine (MESH:D013831), lactose (MESH:D007785)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC11895493/full.md

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Source: https://tomesphere.com/paper/PMC11895493