# A Rare Case of Giant Uterine Leiomyomata: A Difficult Diagnosis Accompanied by Surgical Difficulties

**Authors:** Efthymia Thanasa, Anna Thanasa, Emmanouil M Xydias, Evangelos Kamaretsos, Gerasimos Kontogeorgis, Ioannis Paraoulakis, Apostolos C Ziogas, Ioannis Thanasas

PMC · DOI: 10.7759/cureus.78764 · Cureus · 2025-02-09

## TL;DR

A 45-year-old woman with no symptoms was found to have a rare giant uterine fibroid, which required complex surgery and highlights the challenges in diagnosing and treating such cases.

## Contribution

Reports a rare case of a giant uterine leiomyoma in an asymptomatic reproductive-age woman, emphasizing diagnostic and surgical challenges.

## Key findings

- A giant uterine leiomyoma weighing over 11.4 kg was diagnosed in an asymptomatic 45-year-old woman.
- Surgical removal required a laparotomy and total abdominal hysterectomy with bilateral salpingectomy and oophorectomy.
- The case highlights the difficulty in diagnosing and managing giant uterine leiomyomas in asymptomatic patients.

## Abstract

Leiomyomas, also known as fibroids, are a group of benign smooth muscle tumors commonly present in premenopausal women. Giant uterine leiomyomas are rare. It is described as giant when it weighs 11.4 kg. This report concerns a 45-year-old, asymptomatic woman of reproductive age who presented for her first gynecological consultation at the clinic of Trikala General Hospital, Greece, for a routine smear and gynecological examination. A large, painless abdominal mass was palpated during the clinical exam, reaching the level of the xiphoid process. Imaging confirmed the clinical diagnosis of a myomatous uterus, and surgical intervention via laparotomy was decided. Intraoperatively, a giant uterine leiomyoma was identified, leading to an abdominal total hysterectomy with bilateral salpingectomy and oophorectomy. A histological examination confirmed the diagnosis. After a five-day hospitalization with an uneventful postoperative recovery, the patient was discharged. This rare case emphasizes the uncommon presentation of a giant uterine leiomyoma in an asymptomatic reproductive-age patient, highlighting the diagnostic and surgical challenges associated with managing such cases.

## Linked entities

- **Diseases:** Leiomyoma (MONDO:0001572)

## Full-text entities

- **Diseases:** benign smooth muscle tumors (MESH:D018235), Giant uterine leiomyomas (OMIM:150699), Leiomyomas (MESH:D007889), myomatous uterus (MESH:D014594), Uterine Leiomyomata (MESH:C535516)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC11895401/full.md

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Source: https://tomesphere.com/paper/PMC11895401