# Multidisciplinary Management of Single Organism Emphysematous Splenitis Without Splenectomy: A Case Report

**Authors:** Suanne C MacConnell, Anand Trivedi

PMC · DOI: 10.7759/cureus.80389 · Cureus · 2025-03-11

## TL;DR

This case report shows that non-surgical treatment can successfully manage a rare spleen infection caused by C. perfringens in an elderly, healthy patient.

## Contribution

The paper presents a novel non-surgical approach to treating emphysematous splenitis without splenectomy in an immunocompetent patient.

## Key findings

- Percutaneous drainage and a prolonged antibiotic regimen successfully treated emphysematous splenitis.
- The patient remained haemodynamically stable and immunocompetent without needing surgery.
- Non-operative management is a viable option for select patients with C. perfringens-induced splenic infection.

## Abstract

Emphysematous splenitis traditionally requires a splenectomy, resulting in life-long consequences for the patient. Clostridium perfringens is often seen in an immunocompromised population. This case demonstrates a multidisciplinary team approach consisting of percutaneous drainage and a prolonged intravenous and oral antibiotic regime, including ceftriaxone and metronidazole, as well as amoxicillin and clavulanic acid, to provide a successful outcome in an elderly immunocompetent female. This negated the need to proceed to the traditional operative management of splenectomy and validates an equitable conservative approach to treat a C. perfringens-induced emphysematous splenic infection. This approach was undertaken and was likely successful secondary to the haemodynamic stability and immunocompetent baseline of the patient. Her immunocompetency could be maintained due to the non-operative management and should therefore be considered if the clinical situation allows.

## Linked entities

- **Chemicals:** ceftriaxone (PubChem CID 5479530), metronidazole (PubChem CID 4173), amoxicillin (PubChem CID 33613), clavulanic acid (PubChem CID 5280980)
- **Species:** Clostridium perfringens (taxon 1502)

## Full-text entities

- **Diseases:** Emphysematous (MESH:D041882)
- **Species:** Homo sapiens (human, species) [taxon 9606], Clostridium perfringens (species) [taxon 1502]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11894861/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11894861/full.md

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Source: https://tomesphere.com/paper/PMC11894861