# Analysis of the therapeutic efficacy of OLIF combined with posterior percutaneous pedicle screw fixation in the treatment of patients with primary lumbar spondylodiscitis

**Authors:** Liang Deng, Yu Zhou, Moliang Xiong, Jihuan Zeng, Caiguang Luo, Jia Guo, Qiang Xiao

PMC · DOI: 10.3389/fsurg.2025.1486695 · Frontiers in Surgery · 2025-02-25

## TL;DR

This study shows that a specific surgical method effectively treats primary lumbar spondylodiscitis by improving pain and recovery outcomes.

## Contribution

The study introduces a combined surgical approach for treating lumbar spondylodiscitis with improved clinical outcomes.

## Key findings

- The surgical technique significantly reduced lower back pain symptoms in patients.
- JOA and VAS scores, as well as ESR and CRP levels, improved significantly post-surgery.
- The method allows thorough debridement, sufficient bone grafting, and reliable fixation.

## Abstract

Primary lumbar spondylodiscitis is a serious condition with an increasing incidence rate.

From January 2021 to June 2023, we adopted a single-stage oblique lateral approach for the debridement of lumbar infection foci, intervertebral bone grafting fusion, tube irrigation drainage, combined with posterior percutaneous pedicle screw fixation for the treatment of primary lumbar spondylodiscitis.

We found that this surgical technique significantly improved the patients' lower back pain symptoms. During postoperative follow-ups at 1, 3, 6, and 12 months, patients showed remarkable improvements in their JOA and VAS scores, as well as in ESR and CRP levels, compared to the preoperative period.

We believe that the single-stage oblique lateral approach for debridement of lumbar infection foci, intervertebral bone grafting fusion, tube irrigation drainage, and combined posterior percutaneous pedicle screw fixation is an ideal treatment method for primary lumbar spondylodiscitis. This technique offers thorough debridement of the infection focus, sufficient bone grafting, safe operation, and reliable fixation.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** infection (MESH:D007239), back pain (MESH:D001416), lumbar spondylodiscitis (MESH:D015299)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC11893554/full.md

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Source: https://tomesphere.com/paper/PMC11893554