# Concomitant Graves' Disease and Ulcerative Colitis

**Authors:** Paige Webeler, Pardis Abdollahi Zarandi, Mani Bashyam

PMC · DOI: 10.7759/cureus.78748 · Cureus · 2025-02-08

## TL;DR

A 36-year-old woman was diagnosed with both Graves' disease and ulcerative colitis at the same time, showing how autoimmune conditions can co-occur.

## Contribution

This case report highlights the rare but important coexistence of Graves' disease and ulcerative colitis in a single patient.

## Key findings

- The patient exhibited simultaneous symptoms of ulcerative colitis and Graves' disease.
- Treatment of Graves' disease led to rapid resolution of both conditions' symptoms.
- This case emphasizes the need to consider multiple autoimmune disorders in patients with systemic symptoms.

## Abstract

It is widely recognized that one autoimmune disorder is sometimes associated with an increased frequency of having another autoimmune condition. However, the simultaneous presentation of Ulcerative colitis and Graves’ disease is an underreported occurrence in the medical literature. We present the case of a previously healthy 36-year-old female who presented with acute symptoms of ulcerative colitis and Graves' disease simultaneously, leading to the diagnosis of both conditions within a short time frame. These diagnoses were supported by colonoscopy findings of diffuse colonic inflammation along with low thyroid-stimulating hormone and elevated thyroxine levels. Her symptoms of both Graves' disease and ulcerative colitis rapidly resolved with treatment of Graves’ disease. This case highlights the significance of developing a broad differential and considering the coexistence of multiple autoimmune conditions when systemic symptoms are present.

## Linked entities

- **Diseases:** Graves' disease (MONDO:0005364), ulcerative colitis (MONDO:0005101)

## Full-text entities

- **Diseases:** Graves' Disease (MESH:D006111), colonic inflammation (MESH:D007249), Ulcerative Colitis (MESH:D003093), autoimmune condition (MESH:D001327)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11893215/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11893215/full.md

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Source: https://tomesphere.com/paper/PMC11893215