# Transcanal Endoscopic Repair of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Anomaly Using Topical Fluorescein

**Authors:** Malak Almalki, Yazeed Aloqailiy, Jihad L Nassar, Renad Alfirm

PMC · DOI: 10.7759/cureus.78738 · Cureus · 2025-02-08

## TL;DR

A child with inner ear anomalies and CSF otorrhea was successfully treated using a new transcanal endoscopic technique with topical fluorescein.

## Contribution

First use of topical fluorescein in transcanal endoscopic repair of CSF otorrhea due to inner ear malformation.

## Key findings

- CSF leak was localized at the oval window using fluorescein during endoscopic exploration.
- The technique successfully repaired the CSF otorrhea without bony dehiscence or erosion.
- Beta trace protein analysis confirmed the CSF leak diagnosis.

## Abstract

An eight-year-old female, known to have sensorineural hearing loss due to inner ear anomalies, presented with a history of recurrent attacks of right acute otitis media complicated by bacterial meningitis. Temporal bone computed tomography showed right middle ear and mastoid effusion without bony dehiscence or erosion, with features of common cavity inner ear anomaly on the right side. Given the patient’s inner ear malformation, cerebrospinal fluid (CSF) otorrhea was suspected. Further evaluation with myringocentesis and beta trace protein analysis confirmed the diagnosis. The patient underwent transcanal endoscopic right ear exploration. Initially, the site of the defect was not revealed; the CSF leak was successfully localized at the oval window, surrounding the stapes footplate. This is the first report, to the best of our knowledge, describing topical fluorescein application in a transcanal endoscopic approach to obliterating CSF otorrhea due to inner ear malformation.

## Linked entities

- **Diseases:** sensorineural hearing loss (MONDO:0010576), acute otitis media (MONDO:0024330), bacterial meningitis (MONDO:0006670)

## Full-text entities

- **Diseases:** Inner Ear Anomaly (MESH:D007759), CSF otorrhea (MESH:D002558), sensorineural hearing loss (MESH:D006319), effusion (MESH:D000080324), bacterial meningitis (MESH:D016920), acute otitis media (MESH:D010033), CSF leak (MESH:D065634)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11893199/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC11893199/full.md

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Source: https://tomesphere.com/paper/PMC11893199