# Effects of pericapsular nerve group block versus local anesthetic infiltration for postoperative analgesia in total hip arthroplasty: A protocol for systematic review and meta-analysis

**Authors:** Lingzhi Rong, Tangqi Qin, Shoujia Yu, Donghang Zhang, Yiyong Wei, Robert Chen, Robert Chen, Robert Chen, Robert Chen, Robert Chen

PMC · DOI: 10.1371/journal.pone.0319102 · PLOS One · 2025-03-10

## TL;DR

This study will compare two pain management techniques after hip surgery to see which is more effective in reducing postoperative pain.

## Contribution

The study introduces a systematic review and meta-analysis protocol to compare PENG block and local anesthetic infiltration for postoperative analgesia.

## Key findings

- The primary outcome will assess the time to first analgesic requirement.
- Secondary outcomes include analgesic consumption, VAS scores, and adverse effects.
- Results will be synthesized using RevMan 5.4 software.

## Abstract

This protocol for a systematic review and meta-analysis aims to provide synthesized evidence to determine whether pericapsular nerve group (PENG) block is superior to local anesthetic infiltration in controlling postoperative pain in total hip arthroplasty.

PubMed, EMBASE, Web of science, and the Cochrane library will be systematically searched from their inception to December 30, 2024. Randomized controlled trials (RCTs) that compared the analgesic effects of PENG block with local anesthetic infiltration for total hip arthroplasty will be included. The time to first analgesics requirement (analgesia duration) will be the primary outcome. Secondary outcomes will include the postoperative analgesics consumption over 24 hours, visual analog scale (VAS) scores at rest and movement, and the incidence of adverse effects. Statistical analysis will be conducted by RevMan 5.4 software.

Ethical approval is not applicable. The results of this study will be publicly published.

CRD42024590888

## Full-text entities

- **Diseases:** postoperative pain (MESH:D010149), hip arthroplasty (MESH:D025981)

## Full text

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## Figures

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## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC11893113/full.md

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Source: https://tomesphere.com/paper/PMC11893113