# Managing elderly patients with dual metastatic cancers—navigating diagnostic and treatment challenges

## TL;DR

This paper discusses the treatment of a patient with two metastatic cancers, prostate and colorectal, who achieved remission using a combined therapy.

## Contribution

The novelty lies in demonstrating a successful chemohormonal regimen for dual metastatic cancers in an elderly patient with comorbidities.

## Key findings

- A patient with metastatic prostate and colorectal cancers achieved complete remission of liver and lung metastases.
- The chemohormonal regimen used was effective in managing both malignancies simultaneously.

## Abstract

Prostate and colorectal adenocarcinoma are among the most common primary cancer diagnoses in the United States, with 29% of new cancer diagnoses among adult men in 2024 expected to arise from the prostate and another 15% across men and women being colorectal in origin. Given therapeutic advancements leading to improved survival, individuals with prostate cancer have the highest estimated probability of concurrent secondary primary malignancy. This represents a clinical dilemma as the treatment for each is distinct and impacted by histology, stage, and molecular findings. Herein, we describe a patient with significant comorbidities, found to have simultaneous metastatic prostate and colorectal adenocarcinomas, who achieved sustained complete remission of liver and lung metastases with a chemohormonal regimen.