# The nuclear factor E2-related factor 2 and age-related macular degeneration

## TL;DR

This paper explores how the nuclear factor E2-related factor 2 helps prevent age-related macular degeneration by maintaining redox balance.

## Contribution

The paper highlights the role of nuclear factor E2-related factor 2 in preserving vision through antioxidant enzymes.

## Key findings

- Nuclear factor E2-related factor 2 is crucial for maintaining redox balance.
- Its activation leads to antioxidant enzymes that prevent macular degeneration.
- Understanding this pathway may aid in developing new treatments for vision loss.

## Abstract

After the discovery of anti-vascular endothelial growth factor agents as
treatment of wet age-related macular degeneration, the number of studies with
the objective to understand the molecular mechanisms involved in the age-re
lated macular degeneration genesis has increased. The importance of the nuclear
factor e2-related factor 2 lies in its activation-derived proteins being
involved in the maintenance of the redox balance and consequent prevention of
degenerative macular disease. This article aims to present the characteristics
of nuclear factor e2-related factor 2 and describe the main nuclear factor
e2-related factor 2-activated antioxidant enzymes that contribute to the
preservation of vision.