# Expression of concern: Recyclable mesalamine-functionalized magnetic nanoparticles (mesalamine/GPTMS@SiO2@Fe3O4) for tandem Knoevenagel–Michael cyclocondensation: grinding technique for the synthesis of biologically active 2-amino-4H-benzo[b]pyran derivatives

**Authors:** Mahdiyeh Partovi, Sobhan Rezayati, Ali Ramazani, Yavar Ahmadi, Hooman Taherkhani

PMC · DOI: 10.1039/d5ra90023a · RSC Advances · 2025-03-10

## TL;DR

This paper addresses concerns about a study on using magnetic nanoparticles for a chemical reaction to make biologically active compounds.

## Contribution

The paper raises an expression of concern regarding the original study's methodology or findings.

## Key findings

- The paper highlights potential issues with the original research on magnetic nanoparticle synthesis.
- It questions the validity or reproducibility of the reported chemical reaction results.

## Abstract

Expression of concern for ‘Recyclable mesalamine-functionalized magnetic nanoparticles (mesalamine/GPTMS@SiO2@Fe3O4) for tandem Knoevenagel–Michael cyclocondensation: grinding technique for the synthesis of biologically active 2-amino-4H-benzo[b]pyran derivatives’ by Mahdiyeh Partovi et al., RSC Adv., 2023, 13, 33566–33587, https://doi.org/10.1039/D3RA06560J.

## Linked entities

- **Chemicals:** mesalamine (PubChem CID 4075), SiO2 (PubChem CID 24261)

## Full text

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Source: https://tomesphere.com/paper/PMC11891874