# Pasteurella multocida Spondylodiscitis in an Immunocompetent Patient

**Authors:** Débora A Alves, João Trêpa, Isabel Ramos, Cristina Valente

PMC · DOI: 10.7759/cureus.78602 · Cureus · 2025-02-06

## TL;DR

An 82-year-old immunocompetent woman developed a rare spinal infection caused by Pasteurella multocida, which was successfully treated with antibiotics and physical rehabilitation.

## Contribution

This case highlights the rare occurrence of Pasteurella multocida spondylodiscitis in an immunocompetent individual.

## Key findings

- Pasteurella multocida was identified as the causative agent of spondylodiscitis in an immunocompetent patient.
- The patient showed significant clinical and radiological improvement after eight weeks of intravenous ceftriaxone treatment.
- No surgical intervention was required, and the patient achieved full functional recovery.

## Abstract

We present the case of an 82-year-old woman, previously independent in activities of daily living, who developed fever, myalgias, and headache over one week. Two weeks earlier, she had been treated with antibiotics for a lower respiratory tract infection. The patient had no history of immunosuppression and was a pet owner. She was admitted to the emergency department (ED) with a fever and multiple perforating wounds on her hands. Laboratory findings revealed elevated inflammatory markers, including C-reactive protein and procalcitonin, without an obvious infectious source. During observation and further investigations in the ED, her clinical condition rapidly deteriorated, requiring vasopressor support and subsequent transfer to the intensive care unit (ICU). Blood and urine cultures were obtained, and empirical broad-spectrum antibiotics were initiated. In the ICU, the patient developed severe neck pain with functional limitations. Cervical magnetic resonance imaging (MRI) revealed spondylodiscitis with C3-C4-C5 paramedian epidural empyema. Blood cultures identified Pasteurella multocida, and the patient was treated with intravenous ceftriaxone (2g every 12 hours) for eight weeks. A follow-up MRI at the end of treatment showed significant improvement, with a marked reduction in empyema and no need for surgical intervention. The patient was managed with a cervical collar and physical rehabilitation. At discharge, she had made substantial functional recovery, with no neurological deficits, and her inflammatory markers had returned to baseline.

## Linked entities

- **Species:** Pasteurella multocida (taxon 747)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** neurological deficits (MESH:D009461), neck pain (MESH:D019547), respiratory tract infection (MESH:D012141), Spondylodiscitis (MESH:D015299), headache (MESH:D006261), Pasteurella multocida (MESH:D010326), fever (MESH:D005334), inflammatory (MESH:D007249), myalgias (MESH:D063806), empyema (MESH:D004653)
- **Chemicals:** ceftriaxone (MESH:D002443)
- **Species:** Homo sapiens (human, species) [taxon 9606], Pasteurella multocida (species) [taxon 747]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11889447/full.md

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Source: https://tomesphere.com/paper/PMC11889447