# Central Dentinogenic Ghost Cell Tumor: A Rare Entity

**Authors:** Mary Nashashibi, Amir Farah, Imad Abu El-Naaj, Munir Nashashibi

PMC · DOI: 10.7759/cureus.78556 · Cureus · 2025-02-05

## TL;DR

This paper presents a rare case of a central dentinogenic ghost cell tumor in a 66-year-old man, highlighting its diagnosis and treatment.

## Contribution

The contribution is a detailed clinical and histological report of a rare central DGCT case with low malignant potential.

## Key findings

- The tumor was diagnosed through radiographic and histologic analysis.
- Classic DGCT features included ghost cells, calcifications, and low proliferation index.
- The tumor was successfully enucleated with local anesthesia.

## Abstract

Odontogenic tumors are rare lesions with varied clinical presentations and behaviors. A dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that can be classified into central (intraosseous) and peripheral (extraosseous) types, with a central DGCT often presenting as a bone-expanding lesion. We report a case of a multimorbid 66-year-old male patient with a central DGCT presenting as a painless, 3 × 5.3 cm expansile mass in the right mandibular body. The patient underwent radiographic and histologic assessment followed by tumor enucleation under local anesthesia, which revealed classic features of the DGCT, including ghost cells, calcifications, and a low proliferation index, consistent with low malignant potential.

## Full-text entities

- **Diseases:** Odontogenic tumors (MESH:D009808), DGCT (MESH:D018126), odontogenic neoplasm (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC11887938/full.md

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Source: https://tomesphere.com/paper/PMC11887938