# Extensive Involvement of the Bilateral Trigeminal Nerve Branch as the Only Imaging Manifestation of IgG4‑Related Ophthalmic Disease

**Authors:** Chendong He, Wei Yang

PMC · DOI: 10.5334/jbsr.3838 · Journal of the Belgian Society of Radiology · 2025-03-03

## TL;DR

A rare eye disease can show up only as thickened nerves in imaging scans.

## Contribution

This case highlights a rare imaging-only presentation of IgG4-related ophthalmic disease.

## Key findings

- IgG4-related ophthalmic disease can manifest solely as trigeminal nerve thickening.
- Imaging may be the only sign of the disease without other typical symptoms.

## Abstract

Teaching point: Immunoglobulin G4‑related ophthalmic disease (IgG4‑ROD) may present only as diffuse thickening of the orbital branches of the trigeminal nerve.

## Full-text entities

- **Diseases:** IgG4-ROD (MESH:D000077733)

## Full text

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## Figures

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## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC11887467/full.md

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Source: https://tomesphere.com/paper/PMC11887467