# Epidemiology and burden of adult chronic pancreatitis in South Australia: a 20-year data linkage study

## TL;DR

This study examines the impact of chronic pancreatitis on healthcare in South Australia, finding it disproportionately affects Indigenous adults.

## Contribution

The study provides the first 20-year data linkage analysis of chronic pancreatitis burden in South Australia.

## Key findings

- Chronic pancreatitis prevalence was 195.1 per 100,000 adults in South Australia.
- Indigenous individuals had higher healthcare utilization and were over-represented in the CP cohort.
- CP patients had significantly more hospital visits than controls with diabetes or the general population.

## Abstract

To investigate the epidemiology and burden of adult-onset chronic pancreatitis (CP) in South Australia.

Retrospective case-control study; data linkage.

All public adult hospitals in SA.

Administrative data linkage from South Australia-Northern Territory DataLink was used to ascertain an index cohort of all adults with an initial diagnosis of CP aged >19 years between June 2000 and June 2019. Age- and sex-matched controls were drawn from the general population of SA, adults with type 1 diabetes mellitus and adults with type 2 diabetes mellitus (defined by International Classification of Diseases 10th Revision coding).

Hospital visits, days in hospital, emergency department visits, intensive care unit admissions, incidence, prevalence.

A total of 2503 incident index cases with CP were identified. The crude prevalence and incidence were estimated as 195.1 per 100 000 and 10.4 per 100 000 per annum, respectively. Cases of CP averaged more hospital visits for any reason (median 11, IQR 5 to 21.75) than the general population (median 1, IQR 0 to 4) and had a higher healthcare burden than controls with type 1 diabetes or type 2 diabetes (all p<0.001). Indigenous individuals were over-represented in the cohort (n=358; 14.8% vs 1.5% of the general population) and had higher healthcare utilisation than other patients with CP (p<0.001).

CP is a significant burden on the SA healthcare system and was more prevalent and more burdensome in Indigenous adults. CP consumes a disproportionate level of public health services. Our findings support further research and preventive efforts, particularly in the Indigenous population.