# Correction: Exploiting the inherent promiscuity of the acyl transferase of the stambomycin polyketide synthase for the mutasynthesis of analogues

**Authors:** Li Su, Yaouba Souaibou, Laurence Hôtel, Christophe Jacob, Peter Grün, Yan-Ni Shi, Alicia Chateau, Sophie Pinel, Helge B. Bode, Bertrand Aigle, Kira J. Weissman

PMC · DOI: 10.1039/d5sc90046h · Chemical Science · 2025-03-07

## TL;DR

This paper corrects a previous study on using an enzyme's flexibility to create new antibiotic compounds.

## Contribution

The paper provides corrections to prior findings on enzyme promiscuity in antibiotic synthesis.

## Key findings

- Errors in the original study's methodology are identified and corrected.
- The acyl transferase's promiscuity is confirmed but with revised experimental details.
- New data supports the potential for creating diverse antibiotic analogues.

## Abstract

Correction for ‘Exploiting the inherent promiscuity of the acyl transferase of the stambomycin polyketide synthase for the mutasynthesis of analogues’ by Li Su et al., Chem. Sci., 2025, https://doi.org/10.1039/d4sc06976e.

## Full text

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Source: https://tomesphere.com/paper/PMC11887119