# Favourable outcome of Fusarium prosthetic valve endocarditis in a patient with an Ebstein anomaly

**Authors:** Scott G. Lee-Jones, Stefan van der Westhuizen, Johannes Taljaard, Nelesh P. Govender, Rubina Razack

PMC · DOI: 10.4102/sajid.v40i1.699 · Southern African Journal of Infectious Diseases · 2025-02-11

## TL;DR

A rare case of fungal heart infection caused by Fusarium solani was successfully treated in a patient with a heart defect called Ebstein’s anomaly.

## Contribution

The case highlights the importance of surgical intervention and comprehensive testing for identifying and treating fungal endocarditis.

## Key findings

- Fusarium solani endocarditis was successfully treated with surgery and targeted therapy.
- Source control and identification of the causative organism were critical for the favorable outcome.
- Histology, culture, and molecular testing are essential for diagnosing fungal infections.

## Abstract

Fungal endocarditis is rare, challenging to diagnose and treat and associated with high mortality. We describe a case of Fusarium solani endocarditis in a patient with Ebstein’s anomaly with a favourable outcome.

We emphasise that surgical intervention with source control of the infective vegetation is still the mainstay of treatment and highlight the importance of submitting infected source material for histology, culture and molecular testing to identify the causative organism.

## Linked entities

- **Diseases:** Ebstein anomaly (MONDO:0009144)

## Full-text entities

- **Diseases:** infected (MESH:D007239), Fungal endocarditis (MESH:D009181), prosthetic valve endocarditis (MESH:D004696), Ebstein anomaly (MESH:D004437)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11886575/full.md

## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC11886575/full.md

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Source: https://tomesphere.com/paper/PMC11886575