# Gallbladder Cancer Manifesting As Cutaneous Metastases: An Uncommon Clinical Scenario

**Authors:** Vanisha Pundir, Itish Patnaik, Rohit Gupta, Bhartendu Bhartendu, Tanmay Jain

PMC · DOI: 10.7759/cureus.78515 · 2025-02-04

## TL;DR

This paper presents a rare case of gallbladder cancer that spread to the skin, highlighting the challenges in diagnosing such uncommon metastases.

## Contribution

The novelty lies in reporting a rare clinical case of cutaneous metastasis from gallbladder cancer and emphasizing the need for increased clinical awareness.

## Key findings

- Cutaneous metastasis from gallbladder carcinoma is exceptionally rare and often misdiagnosed.
- Delayed recognition of cutaneous metastases can hinder timely treatment and worsen outcomes.
- A high index of suspicion is crucial for diagnosing rare metastatic presentations.

## Abstract

Cutaneous metastasis from gallbladder carcinoma is exceptionally rare. Gallbladder carcinoma typically spreads to the liver and lymph nodes, with extra-abdominal metastasis being uncommon. Extra-abdominal metastases may involve sites such as the lungs or CNS. Skin is an infrequent site of metastases. These cutaneous lesions are often misdiagnosed, especially when they precede the diagnosis of malignancy.

We report a rare case of gallbladder carcinoma presenting with cutaneous metastasis in an elderly male. Initially misdiagnosed and treated as a dermatological condition, this case highlights the diagnostic challenges posed by the rarity and diverse clinical manifestations of cutaneous metastases in gallbladder cancer. Limited awareness among clinicians often leads to delayed recognition and treatment. A high index of suspicion is essential for timely diagnosis, enabling early intervention that may help mitigate systemic disease progression and improve patient outcomes.

## Linked entities

- **Diseases:** gallbladder carcinoma (MONDO:0003220)

## Full-text entities

- **Diseases:** cutaneous lesions (MESH:D009059), Cutaneous Metastases (MESH:D009362), disease (MESH:D004194), malignancy (MESH:D009369), Gallbladder Cancer (MESH:D005706)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11884946/full.md

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Source: https://tomesphere.com/paper/PMC11884946