This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction Note: High-mobility group box chromosomal protein-1 deletion alleviates osteoporosis in OVX rat model via suppressing the osteoclastogenesis and inflammation
Haotao Yu, Wei Zhou, Zhihong Zhong, Ruixin Qiu, Guoquan Chen, Ping Zhang

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsBone Metabolism and Diseases · MicroRNA in disease regulation · Osteoarthritis Treatment and Mechanisms
Retraction Note: Journal of Orthopaedic Surgery and Research (2022) 17:232
10.1186/s13018-022-03110-8
The Editor-in-Chief has retracted this article after concerns were raised about the data reported. Specifically:
- The β-actin blot in Fig. 2d appears similar to an image included in Fig. 1k of a prior publication [1], with no common authors.
- The HE panel of WT OVX in Fig. 3a appears similar to an image included in Fig. 5b of a prior publication [2], with no common authors.
- The COI1A1 and DLX2 blots in Fig. 5i appear similar to images included in Fig. 4f of a separate publication with no common authors [3], which was published around the same time as this publication.
The authors were not able to provide raw data for this publication upon request by the Publisher. The Editor-in-Chief no longer has confidence in the findings and conclusions of this article.
The authors did not respond to correspondence from the Publisher regarding this retraction.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Li J, He W, Wang Y, Zhao J, Zhao X. mi R-103a-3p alleviates oxidative stress, apoptosis, and immune disorder in oxygen-glucose deprivation-treated BV 2 microglial cells and rats with cerebral ischemia-reperfusion injury by targeting high mobility group box 1. Ann Transl Med 8 (2). 2020 10.21037/atm-20-5856.10.21037/atm-20-5856 PMC 766189833209876 · doi ↗ · pubmed ↗
- 2Zhao Z, Yang J, Zhang L, Zhou Y. Enhancement of DUSP 14 (dual specificity phosphatase 14) limits osteoarthritis progression by alleviating chondrocyte injury, inflammation and metabolic homeostasis. Bioengineered 12 (1). 2021. 10.1080/21655979.2021.10.1080/21655979.2021.1979355 PMC 880666334605731 · doi ↗ · pubmed ↗
- 3Gong S, Xiong L, Luo Z et al. Retracted article: SIRT 6 promotes ferroptosis and attenuates glycolysis in pancreatic cancer through regulation of the NF κB pathway. Exp Ther Med 24 (502). 2022 10.3892/etm.2024.12751.10.3892/etm.2022.11430 PMC 925796135837046 · doi ↗ · pubmed ↗
