# Navigating the Diagnostic Challenges of Posterior Circulation Ischaemic Strokes: A Case Report of Delayed Diagnosis

**Authors:** Hla Hla Aye, Eluzai Hakim

PMC · DOI: 10.7759/cureus.78403 · Cureus · 2025-02-03

## TL;DR

A case report shows how posterior circulation strokes can be missed due to non-specific symptoms, emphasizing the need for careful evaluation in patients with risk factors.

## Contribution

Highlights diagnostic challenges of posterior circulation ischaemic stroke through a real-world case with delayed diagnosis.

## Key findings

- Non-specific symptoms like vertigo can mask posterior circulation stroke.
- MRI was crucial in identifying small infarcts missed by CT scans.
- Early consideration of stroke in high-risk patients can prevent complications.

## Abstract

Posterior circulation infarcts (POCI) can present with non-specific symptoms, making diagnosis challenging and often delayed. We present a 58-year-old lady with a history of migraine who attended the emergency department of a district general hospital with sudden onset of vertigo, nausea, and vomiting but without focal neurological deficits. At the initial assessment, she experienced marked dizziness, which was worse on opening her eyes. Unenhanced brain computed tomography (CT) scan as well as CT angiography were normal. A provisional diagnosis of atypical presentation of migraine or benign paroxysmal positional vertigo was made. A stroke physician's opinion was sought, and in view of her persistent symptoms, magnetic resonance imaging (MRI) brain was carried out. This demonstrated three small acute infarcts: one in the posterior left temporal lobe, one in the inferior left occipital lobe, and one in the left cerebellar vermis. Further comprehensive stroke investigations were unremarkable. She was treated with dual antiplatelet therapy and statin. This case highlights the diagnostic challenges of posterior circulation ischaemic stroke and the importance of considering it in patients with unexplained vertigo, particularly those with stroke risk factors (migraine with aura, elevated cholesterol, and family history of stroke in this patient), to prevent misdiagnosis and serious complications.

## Linked entities

- **Diseases:** migraine (MONDO:0005277), stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** neurological deficits (MESH:D009461), stroke (MESH:D020521), ischaemic stroke (MESH:D002544), POCI (MESH:D020520), vomiting (MESH:D014839), infarcts (MESH:D007238), migraine with aura (MESH:D020325), migraine (MESH:D008881), vertigo (MESH:D014717), dizziness (MESH:D004244), benign paroxysmal positional vertigo (MESH:D065635), nausea (MESH:D009325)
- **Chemicals:** antiplatelet (-), cholesterol (MESH:D002784)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11880866/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11880866/full.md

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Source: https://tomesphere.com/paper/PMC11880866