# Nutritional therapy for MRSA sepsis complicated with pulmonary embolism in children under limited energy and nutrient conditions: a case report

**Authors:** Lin Kong, Li Xia, Fang Zhou, Tian Tan, Zhongmin Gao, Bo Zhou, Yao Jiang, Chengjun Liu, Dandan Pi

PMC · DOI: 10.3389/fnut.2025.1484012 · Frontiers in Nutrition · 2025-02-19

## TL;DR

This case report describes the nutritional management of a child with MRSA sepsis and pulmonary embolism under limited energy and nutrient conditions.

## Contribution

The paper presents a novel approach to nutritional therapy in a complex pediatric case involving MRSA sepsis and pulmonary embolism.

## Key findings

- Permissive low-calorie enteral nutrition was effective in the early stages of treatment.
- Supplementary parenteral nutrition improved the patient's condition while managing fluid restrictions and coagulation issues.
- The patient showed significant clinical improvement and wound healing.

## Abstract

The nutritional treatment of methicillin-resistant Staphylococcus aureus sepsis combined with pulmonary embolism presents considerable challenges due to the risks associated with tube placement, coagulation disorders, severe infections, digestive limitations, and fluid restrictions in pediatric patients. This report discusses the case of an approximately 13-year-old female patient admitted with symptoms of right lower limb pain, fever, and cough accompanied by shortness of breath. The patient was assessed to be at moderate risk of malnutrition. In the early stages of treatment, permissive low-calorie enteral nutrition was administered alongside clinical interventions such as anti-infection therapy, anticoagulation, and empyema drainage. In the later stages, supplementary parenteral nutrition therapy was introduced, with careful monitoring of fluids restrictions, infection control, and coagulation index improvements. The patient’s condition improved significantly, and the wounds on the right chest and back healed well. A retrospective review of the literature over the past decade was conducted using domestic and international databases, alongside an analysis of current guidelines for nutritional support in critically ill children.

## Linked entities

- **Diseases:** pulmonary embolism (MONDO:0005279), malnutrition (MONDO:0006873)

## Full-text entities

- **Diseases:** sepsis (MESH:D018805), shortness of breath (MESH:D004417), cough (MESH:D003371), malnutrition (MESH:D044342), pain (MESH:D010146), coagulation disorders (MESH:D001778), critically ill (MESH:D016638), fever (MESH:D005334), pulmonary embolism (MESH:D011655), empyema (MESH:D004653), infection (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606], Staphylococcus aureus (species) [taxon 1280]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11879809/full.md

## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC11879809/full.md

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Source: https://tomesphere.com/paper/PMC11879809