# Left main stem disease: percutaneous coronary intervention vs. coronary artery bypass grafting—what about medical management? A case report

**Authors:** Edyta Kaczmarska-Dyrda, Piotr Nikodem Rudziński, Mariusz Dębski, Zofia Dzielińska, Marcin Demkow

PMC · DOI: 10.1093/ehjcr/ytaf072 · European Heart Journal. Case Reports · 2025-02-14

## TL;DR

A case report compares treatment options for left main coronary artery disease, highlighting the evolving role of PCI as an alternative to CABG.

## Contribution

Presents a case where PCI is considered a compelling alternative to CABG for left main bifurcation stenosis.

## Key findings

- PCI is increasingly viable for treating LMCA bifurcation stenosis in selected patients.
- Current guidelines still favor CABG, but PCI has made significant progress.
- Successful PCI of complex LMCA lesions is now technically feasible.

## Abstract

Optimal strategy for treating bifurcation lesions in the left main coronary artery (LMCA) remains elusive.

We describe a 66-year-old Caucasian male with a risk factor for coronary artery disease, but free of angina, who presented to the hospital after syncope and nsVT diagnosis in the 24 h Holter electrocardiography monitoring. Coronary computed tomography angiography revealed LMCA bifurcation stenosis with concomitant left circumflex artery (LCx) and diagonal branch stenosis. Subsequent coronary angiography confirmed diagnosis. Successful percutaneous coronary intervention (PCI) of bifurcation/distal LMCA disease involving ostium of LAD and LCx has been a challenging procedure.

Current guidelines still favour coronary artery bypass grafting (CABG) over PCI for revascularization in LMCA stenosis. However, great progress has been made on PCI; therefore, it has become the compelling alternative procedure to CABG for the LMCA bifurcation stenosis in appropriately selected patients.

## Linked entities

- **Diseases:** coronary artery disease (MONDO:0005010)

## Full-text entities

- **Diseases:** syncope (MESH:D013575), bifurcation lesions (MESH:C537283), left circumflex artery (LCx) and diagonal branch stenosis (MESH:D012078), LMCA bifurcation stenosis (MESH:D003324), angina (MESH:D000787)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11879461/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC11879461/full.md

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Source: https://tomesphere.com/paper/PMC11879461