# Five challenging presentations of juvenile nasopharyngeal angiofibroma: our experience in the diagnosis and endoscopic surgical management

**Authors:** Danah Alrusayyis, Jood K Alotaibi, Rahaf Almutarii, Fadhel M Almolani, Mohammed Al-Ahmari, Abdulrahman Alkhatib, Ali Almomen

PMC · DOI: 10.1093/jscr/rjaf055 · Journal of Surgical Case Reports · 2025-02-28

## TL;DR

This paper discusses the diagnosis and endoscopic surgical treatment of five complex cases of juvenile nasopharyngeal angiofibroma in young male patients.

## Contribution

The study highlights the effectiveness of a two-surgeon transseptal endoscopic approach for challenging JNA cases.

## Key findings

- Complete or near-complete tumor resection was achieved in all five cases using endoscopic techniques.
- A two-surgeon transseptal approach was effective for large tumors, avoiding external resection.
- One patient required a revision endoscopic excision after tumor regrowth during follow-up.

## Abstract

Juvenile nasopharyngeal angiofibroma (JNA) is a benign tumor originating from the pterygopalatine fossa and is the most common lesion of the nasopharynx. Its hypervascularity and complex anatomical extensions make selecting the most effective surgical approach intricate. All patients in this series were males, and their age ranged between 8 and 23 years. Extensions to the carotids, cavernous sinus, and infratemporal fossa were noted. In addition, intraoperative details with particular emphasis on the endoscopic two-surgeon transseptal approach were discussed. Nasal obstruction was the most reported symptom, whereas epistaxis was evident in two cases. Complete or near-complete resection of the tumor was achieved in all cases. Over the follow-up period, one patient underwent successful revision endoscopic excision after tumor regrowth. JNA can be completely excised with endoscopic techniques. For large tumors, creating a wider window by using a two-surgeon trans-septal approach is practical and defers the need for external resection.

## Linked entities

- **Diseases:** juvenile nasopharyngeal angiofibroma (MONDO:0017340)

## Full-text entities

- **Diseases:** epistaxis (MESH:D004844), Nasal obstruction (MESH:D015508), JNA (MESH:D018322), benign tumor (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11879101/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11879101/full.md

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Source: https://tomesphere.com/paper/PMC11879101