# A case of permanent vision loss due to a carotidcavernous fistula: importance of early diagnosis

**Authors:** Ítalo Pena de Oliveira, Francyne Veiga Reis Cyrino, Sheila Andrade de Paula Cecchetti, Carlos Yuji Nunomura, Patricia Mitiko Santello Akaishi, Rodrigo Jorge

PMC · DOI: 10.5935/0004-2749.20220054 · Arquivos Brasileiros de Oftalmologia · 2025-08-21

## TL;DR

A 97-year-old woman experienced permanent vision loss from a carotid-cavernous fistula due to delayed diagnosis despite early symptoms.

## Contribution

Highlights the importance of early clinical suspicion for carotid-cavernous fistula in patients with palpebral hyperemia and edema.

## Key findings

- Delayed diagnosis of carotid-cavernous fistula led to irreversible vision loss despite embolization.
- Initial symptoms like palpebral hyperemia and edema can indicate carotid-cavernous fistula.
- Early detection is critical to prevent permanent visual damage.

## Abstract

A 97-year-old female presented with spontaneous acute-onset palpebral hyperemia
and edema of the right eye that had progressively worsen over the previous three
days. These signs did not suggest possible carotid-cavernous fistula until a
second examination 72 h later, during which the patient exhibited significant
progression. Despite embolization, the patient exhibited sustained corneal
edema, clots, and turbidity in the aqueous humor, which resulted in permanent
visual loss. A greater level of clinical suspicion for possible
carotid-cavernous fistula is warranted on initial presentation of palpebral
hyperemia and edema to prevent possible irreversible vision loss.

## Full-text entities

- **Diseases:** palpebral hyperemia (MESH:D006940), vision loss (MESH:D014786), embolization (MESH:D004617), corneal edema (MESH:D015715), carotidcavernous fistula (MESH:D005402), edema (MESH:D004487), carotid-cavernous fistula (MESH:D020216)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11878405/full.md

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Source: https://tomesphere.com/paper/PMC11878405