# Ossifying fibroma of the nasal cavity: Case report and literature review

## TL;DR

This case report describes a rare occurrence of ossifying fibroma in the nasal cavity of a 25-year-old woman with a history of B-cell lymphoma.

## Contribution

The novelty lies in presenting an uncommon location (nasal cavity) for ossifying fibroma, which is typically found in the jaw.

## Key findings

- Ossifying fibroma in the nasal cavity is rare and can extend to adjacent sinuses without causing bony destruction.
- Surgical removal is the primary treatment to prevent recurrence, as incomplete resection may lead to regrowth.
- The lesion was asymptomatic until it reached a size causing detectable abnormalities on imaging.

## Abstract

Ossifying fibroma is a benign, encapsulated, or demarcated neoplasm consisting of varying amounts of cementum-like tissue or bone within a fibrous tissue stroma. It commonly affects patients aged 20 to 40 years, with a predominance in females; however, it can also affect children and adolescents. In this case report, we will present a rare instance of ossifying fibroma in the nasal cavity.

A 25-year-old female, a known case of B-cell lymphoma diagnosed in 2022 and treated with chemotherapy, was referred to ENT for an abnormal CT finding. The CT showed a complex lesion in the left nasal cavity with peripheral calcification and extension to the left maxillary sinus, left frontal sinus, and ethmoidal air cells. The remaining paranasal sinuses were well-aerated, and no associated bony destruction was found.

The appearance of ossifying fibroma lesions in the nasal cavity is uncommon. In the literature, most cases of ossifying fibroma are typically found in sites such as the mandible and maxilla. It usually present as a painless bony mass that can give rise to symptoms depending on the site affected. The mainstay management is primarily surgical. It is suggested that without complete removal of the lesion, recurrence can occur between 6 months to 7 years after resection.

Ossifying fibroma is a benign bony lesion that most commonly affects the mandible and maxilla. It primarily occurs in females during their second to fourth decades of life. Such lesions are usually asymptomatic until they grow large enough to cause symptoms. Management for such tumor is primarily surgical to avoid recurrence.

•Ossifying fibromas usually occur in sites such as the mandible. However, their appearance in the nasal cavity is uncommon.•Ossifying fibromas are often asymptomatic until they grow large enough to produce noticeable swelling and deformity.•The management of ossifying fibroma is primarily surgical due to the tendency of these lesions to recur.

Ossifying fibromas usually occur in sites such as the mandible. However, their appearance in the nasal cavity is uncommon.

Ossifying fibromas are often asymptomatic until they grow large enough to produce noticeable swelling and deformity.

The management of ossifying fibroma is primarily surgical due to the tendency of these lesions to recur.