Labial adhesions due to vulvovaginal lichen planus suspected to be caused by angiotensin II receptor blocker

TL;DR

A 78-year-old woman's labial adhesions were likely caused by a medication, and stopping the drug resolved her symptoms and prevented recurrence.

Contribution

Identifies angiotensin II receptor blockers as a potential cause of labial adhesions via lichenoid drug eruption.

Findings

Discontinuation of the drug led to rapid resolution of vulvodynia and itching.

Pathology improved, and labial adhesions did not recur after detachment.

Angiotensin II receptor blockers may cause vulvovaginal erosive lichen planus.

Abstract

Lichenoid drug eruption, induced by gold or cardiovascular drugs, is one of the causes of lichen planus, and vulvovaginal erosive lichen planus can cause labial adhesions. However, few studies have focused on drugs as a cause of labial adhesions.

We encountered a 78‐year‐old woman with labial adhesions, vulvodynia, and itching of the vulva. The cause was thought to be lichenoid drug eruption from an angiotensin II receptor blocker. After discontinuation of the drug, vulvodynia and pruritus resolved quickly, the pathology showed improvement, and labial adhesions did not recur after detachment.

An angiotensin II receptor blocker was a suspected cause of vulvovaginal erosive lichen planus, which causes labial adhesions. Physicians should recognize the possible cause of labial adhesions secondary to lichenoid drug eruption.

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