# A case of seminal vesicle metastasis from bilateral seminoma

**Authors:** Yusuke Aida, Yosuke Yasuda, Emiko Sugawara, Kosuke Takemura, Yusuke Yoneoka, Ryo Fujiwara, Tomohiko Oguchi, Noboru Numao, Junji Yonese, Takeshi Yuasa

PMC · DOI: 10.1002/iju5.12813 · 2024-12-22

## TL;DR

This paper reports a rare case of a 52-year-old man with seminoma that recurred in the seminal vesicle 8 years after surgery.

## Contribution

The novelty is the first documented case of seminal vesicle metastasis after bilateral orchiectomy for testicular seminoma.

## Key findings

- The patient was diagnosed with left seminal vesicle metastasis 8 years after initial orchiectomy.
- Treatment with bleomycin, etoposide, and cisplatin led to no abnormal signals in the seminal vesicle on imaging.
- This is the first reported case of such a recurrence in the seminal vesicle.

## Abstract

Postoperative recurrence of seminoma is often seen in lungs, liver, and retroperitoneal lymph nodes, such as the para‐aortic lymph nodes. Most of these recurrences (>90%) occur in the first 3 years after orchiectomy. We report a case of a single recurrence in the seminal vesicle after bilateral radical orchiectomies for metachronous bilateral testicular seminoma.

A 52‐year‐old patient with a past history of bilateral testicular seminoma was diagnosed with left seminal vesicle metastasis by magnetic resonance imaging followed by needle biopsy 8 years after the first orchiectomy. After four cycles of bleomycin, etoposide, and cisplatin regimen were administered, FDG‐18 positron emission tomography‐computed tomography showed no abnormal signal in the left seminal vesicle.

To the best of our knowledge, this is the first report of seminal vesicle metastasis following radical orchiectomies for bilateral testicular seminoma.

## Linked entities

- **Chemicals:** bleomycin (PubChem CID 5360373), etoposide (PubChem CID 36462), cisplatin (PubChem CID 5460033)
- **Diseases:** seminoma (MONDO:0003001), testicular seminoma (MONDO:0003669)

## Full-text entities

- **Diseases:** seminal vesicle metastasis (MESH:C537244), seminoma (MESH:D018239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11872200/full.md

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Source: https://tomesphere.com/paper/PMC11872200