Frequency of Human Papillomavirus Genotypes among Women with Genital Wart Using Molecular Hybridization Methods
Zahra Shahriyari, Mohammad Niakan, Zahra Soleimani

TL;DR
This study analyzed HPV genotypes in women with genital warts in Tehran and found that low-risk HPV types, especially type 6, were most common.
Contribution
The study provides new data on the prevalence of specific HPV genotypes in genital warts in a specific geographic region using molecular hybridization.
Findings
HPV was detected in all 67 women with genital warts.
HPV type 6 was the most common low-risk genotype (44.77%), and type 16 was the most common high-risk genotype (5.97%).
16 cases involved multiple HPV infections.
Abstract
Human papillomavirus (HPV) is one of the most common sexually transmitted infections worldwide, which can lead to virus-related cancers. This study aimed to investigate the frequency of HPV genotypes in women with genital warts referred to available laboratories in Tehran by molecular hybridization method. This cross-sectional descriptive study was conducted on the genital warts of 67 women aged 20-50, who were referred to the clinics of Afshar, Namad, Mani, and Al-Mohammed in Tehran province. Viral DNA was extracted using Add prep genomic DNA extraction kit, and genotyping was studied using HPV Direct Flow CHIP Kit. Data were analyzed by GraphPad Prism software. HPV was reported to be positive in all cases. The most common low-risk genotype involved was type 6, with 30 cases (44.77%), and the most common high-risk genotype involved was type 16, with 4 cases (5.97%) in the total…
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Taxonomy
TopicsCervical Cancer and HPV Research
