# Self-Assembled PVP-Gd Composite Nanosheets via Ultrasound Synthesis for Targeted Acrylamide Sensing in Food Safety

## TL;DR

This paper introduces a new sensor made of nanosheets that can detect acrylamide, a harmful chemical in food, with high sensitivity and accuracy.

## Contribution

A novel ultrasound-synthesized PVP-Gd nanosheet platform for targeted acrylamide sensing with a low detection limit.

## Key findings

- The PVP-Gd nanosheets show robust blue fluorescence with a quantum yield of 45.01%.
- The sensor has a low detection limit of 9.4 nM and a broad linear response range for acrylamide.
- The synthesis process was optimized using a full factorial design, revealing significant parameter interactions.

## Abstract

Acrylamide (AM) is a recognized carcinogen and neurotoxin,
posing
a significant threat to food safety and human health. Therefore, developing
sensitive and convenient methods for AM detection in food samples
is essential. This study responds to the urgent need for sensitive
and selective detection of AM, a hidden hazard in food, to safeguard
public health and environmental safety. We present the development
of a novel two-dimensional ultrasound-synthesized PVP-Gd composite
nanosheet platform for precise AM sensing. These self-assembled nanosheets,
constructed from gadolinium (Gd) and poly(vinylpyrrolidone) (PVP),
exhibit remarkable stability and robust blue fluorescence, with a
quantum yield of 45.01% upon excitation at 380 nm. A full factorial
design was employed to optimize the synthesis process, revealing significant
parameter interactions. The optimized nanosheets demonstrated a strong
quenching effect upon acrylamide exposure, resulting in a high-performance
acrylamide sensor with an impressively low detection limit (9.4 nM)
and a broad linear response range. This innovative sensor platform
offers a promising approach for environmental monitoring and food
safety applications, effectively addressing the risks associated with
acrylamide.