# Single center, retrospective evaluation of requiring 48 hours versus 24 hours before a pharmacist-driven protocol-based IV to PO conversion of azithromycin

**Authors:** Abraham Felix, Winifred Pardo, Wilbert Fuerte, Laura Morales, Timothy P. Gauthier

PMC · DOI: 10.1017/ash.2025.8 · Antimicrobial Stewardship & Healthcare Epidemiology : ASHE · 2025-02-26

## TL;DR

Changing a protocol to switch azithromycin from IV to oral after 24 instead of 48 hours increased oral use and reduced hospital stays.

## Contribution

A new protocol reduced the waiting time for IV to PO azithromycin conversion, improving treatment efficiency.

## Key findings

- Switching to oral azithromycin after 24 hours increased oral therapy days by 26%.
- The shorter protocol was associated with reduced hospital length of stay.

## Abstract

Shortening a pharmacist-driven policy to allow a switch from IV to PO azithromycin after 24 hours instead of 48 hours led to 26% increase in oral azithromycin days of therapy (P < 0.001) and was associated with a shorter length of stay.

## Linked entities

- **Chemicals:** azithromycin (PubChem CID 447043)

## Full text

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## Figures

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC11869072/full.md

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Source: https://tomesphere.com/paper/PMC11869072