# Stewarding beyond the 9–5: Implementation of overnight review of rapid blood culture identification panel results by intensive care unit pharmacists

**Authors:** Sarah M. Arduser Sindelar, Jonathan H. Ryder, Jeremy Tigh, Theodore Blum, Jessica Prucha, Paul Fey, Scott J. Bergman, Trevor C. Van Schooneveld, Shawnalyn W. Sunagawa

PMC · DOI: 10.1017/ash.2025.28 · Antimicrobial Stewardship & Healthcare Epidemiology : ASHE · 2025-02-17

## TL;DR

This study shows that having ICU pharmacists review blood culture results overnight improves how quickly patients get proper antibiotic treatment.

## Contribution

The novel contribution is implementing overnight review of blood culture results by ICU pharmacists to improve antimicrobial stewardship outside regular hours.

## Key findings

- Overnight review reduced time to evaluation from 9.3 to 3.6 hours.
- The change was statistically significant (P < .01).

## Abstract

Rapid blood culture identification is most effective with antimicrobial stewardship feedback, which is limited during non-business hours. We implemented overnight review of Blood Culture Identification 2 panel results by intensive care unit pharmacists and demonstrated reduced time to evaluation (3.6 vs 9.3 hours, P < .01).

## Full-text entities

- **Genes:** ASPM (assembly factor for spindle microtubules) [NCBI Gene 259266] {aka ASP, Calmbp1, MCPH5}
- **Diseases:** AIDS (MESH:D000163), Staphylococcus aureus bacteremia (MESH:D013203), Infections (MESH:D007239), ID (MESH:D003141), ill (MESH:D002908), bloodstream infections (MESH:D018805), HIV (MESH:D015658)
- **Species:** Staphylococcus epidermidis (species) [taxon 1282], Serratia marcescens (species) [taxon 615], Lodderomyces parapsilosis (species) [taxon 5480], Staphylococcus aureus (species) [taxon 1280], Saccharomyces cerevisiae (baker's yeast, species) [taxon 4932], Escherichia coli (E. coli, species) [taxon 562], Streptococcus pneumoniae (species) [taxon 1313], Enterococcus faecalis (species) [taxon 1351], Bacteroides fragilis (species) [taxon 817], Staphylococcus lugdunensis (species) [taxon 28035], Haemophilus influenzae (species) [taxon 727], Klebsiella oxytoca (species) [taxon 571], Candida albicans (species) [taxon 5476], Acinetobacter baumannii (species) [taxon 470], Homo sapiens (human, species) [taxon 9606], Nakaseomyces glabratus (species) [taxon 5478], Klebsiella aerogenes (species) [taxon 548], Streptococcus pyogenes (species) [taxon 1314], Enterobacter cloacae (species) [taxon 550], Streptococcus agalactiae (species) [taxon 1311]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11869055/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11869055/full.md

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Source: https://tomesphere.com/paper/PMC11869055