The use of a woman’s own eggs in her first IVF treatment at the age of 48 years and 10 months with successful live birth after PGT-A: a case report

TL;DR

A 48-year-old woman successfully had a baby using her own eggs and IVF with a normal embryo, showing it's possible in rare cases.

Contribution

This case report highlights a rare successful IVF outcome using a woman's own eggs at an advanced maternal age.

Findings

A 48-year-old woman achieved a clinical pregnancy and live birth using her own eggs and IVF.

The pregnancy resulted from a euploid embryo selected through PGT-A.

The case suggests limited IVF attempts with a woman's own eggs may be viable in specific situations.

Abstract

Natural conception in women after the age of 45 years is rare. The probability of
successful pregnancy in this specific group of women after IVF and embryo
transfer with autologous oocytes is also reduced. In addition, advanced maternal
age is associated with an increased risk of aneuploidies and other associated
complications during pregnancy. Generally, women who are over 44 years old are
advised to receive IVF treatment with donated oocytes due to poor oocyte quality
and low ovarian reserve. Although IVF outcomes in women of advanced age can be
associated with the best prognosis when donated oocytes are used, IVF is not
always well accepted by infertile couples. This is a case report of a woman who
achieved a clinical pregnancy and live birth in her first attempt at IVF
treatment with her own eggs and a euploid embryo at 48 years and 10 months,
respectively, at the time of oocyte retrieval. This case demonstrates that
limited attempts at assisted reproductive technology with older women’s own eggs
may be an option in specific cases.

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