# Skull Oligometastasis From Cervical Cancer: A Case Report

**Authors:** Safaa M Alshakankery, Tawfeeq A Tawfeeq, Husam S Almuhaish, Sultan Alsaiari, Mahmoud I Hadad, Marwah Abdulkader

PMC · DOI: 10.7759/cureus.78115 · 2025-01-28

## TL;DR

A case report describes a rare cervical cancer metastasis to the skull, highlighting the importance of early diagnosis and palliative care.

## Contribution

This case report presents a rare instance of cervical cancer metastasizing to the skull and emphasizes the need for timely intervention.

## Key findings

- A 46-year-old woman with cervical cancer developed a metastatic lesion in the occipital bone.
- Imaging confirmed a lytic lesion without intraparenchymal involvement, and no other metastases were found.
- Surgical resection and pathological analysis confirmed metastatic squamous cell carcinoma of cervical origin.

## Abstract

Bone metastasis is common, mostly resulting from hematogenous spread and usually carrying significant morbidity. The clinical presentation of bone metastasis depends on the site of metastasis and the involved structures. Radiological studies are usually able to detect the location and extent of the lesions with high accuracy. Management of bone metastasis is often a challenging mission. Here, we highlight the case of a 46-year-old postmenopausal lady who was diagnosed with cervical squamous cell carcinoma (SCC), human papillomavirus (HPV)-associated, and International Federation of Gynecology and Obstetrics (FIGO) stage IIIC1, after she presented with postcoital and irregular vaginal bleeding. The patient received chemoradiotherapy. Two months following treatment completion, she complained of painful occipital swelling. Computerized tomography (CT) of the brain revealed an occipital bone lytic lesion without intraparenchymal involvement, which was confirmed by magnetic resonance imaging (MRI). positron emission tomography-computed tomography (PET-CT) and nuclear bone scans excluded other sites of recurrences. She underwent surgical resection for this occipital lesion. The pathological analysis has confirmed the diagnosis of metastatic SCC of cervical origin. Given the poor prognosis of cervical cancer with bone metastasis, early diagnosis and proper palliative treatment probably preserve the quality of the patient’s life despite the expected poor survival rate.

## Linked entities

- **Diseases:** cervical cancer (MONDO:0002974), squamous cell carcinoma (MONDO:0005096)

## Full-text entities

- **Diseases:** International Federation of Gynecology and Obstetrics (MESH:D005831), painful (MESH:D010146), Bone metastasis (MESH:D009362), bone lytic lesion (MESH:D001847), occipital lesion (MESH:D006259), vaginal bleeding (MESH:D014592), Cervical Cancer (MESH:D002583), SCC (MESH:D002294)
- **Species:** Human papillomavirus (species) [taxon 10566], Homo sapiens (human, species) [taxon 9606]

## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11866034/full.md

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Source: https://tomesphere.com/paper/PMC11866034