# Mixed Glioneural Tumors Mimicking Gliomas: Two Cases From a Tertiary Care Institute in South India and a Literature Review

## TL;DR

This paper presents two rare brain tumor cases that resemble gliomas but have better outcomes, emphasizing the importance of accurate diagnosis and treatment.

## Contribution

The paper adds two new clinical cases and a literature review to improve understanding of mixed glioneural tumors in South India.

## Key findings

- Both patients had successful surgical outcomes and no neurological complaints during follow-up.
- The study highlights the need for careful differentiation between glioneuronal tumors and gliomas for appropriate treatment.
- Adjuvant radiation was used, but its role in treatment remains unclear.

## Abstract

Glioneuronal tumours are rare neural neoplasms that show differentiation and are usually low-grade. Unlike gliomas, they do not require aggressive management, and diagnosing and differentiating between these two entities is crucial to determining the treatment paradigm of this disease. Surgery is the treatment of choice for glioneuronal tumours, and the role of adjuvant treatment still needs to be fleshed out. These two cases, involving a six-year-old female child and a 35-year-old male patient, highlight the need to be cautious while differentiating these entities from their equivalents with poorer prognoses. They both underwent surgery followed by adjuvant radiation, with subsequent neuroimaging at regular intervals. Both patients were devoid of neurological complaints at the time of follow-up. These cases and literature review delve into the minutiae of clinical manifestations, histopathological characteristics, various modalities of treatment, and treatment outcomes of glioneuromas.