# A Pelvic Mass in a Young Patient With Crohn's Disease

## TL;DR

This paper presents a rare case of a young patient with both Crohn's disease and unicentric Castleman disease, highlighting their shared inflammatory pathways.

## Contribution

The novelty lies in reporting a rare coexistence of unicentric Castleman disease and Crohn's disease in a young patient.

## Key findings

- The patient had both unicentric Castleman disease and Crohn's disease.
- Interleukin-6 is a shared proinflammatory factor in both diseases.
- This case suggests a potential common therapeutic target for both conditions.

## Abstract

Castleman disease (CD) is a rare group of lymphoproliferative disorders subdivided based on clinical features. Although not fully understood, the pathogenesis of both CD and Crohn's disease involves a combination of immune dysregulation and infectious and environmental factors. Interleukin-6, a proinflammatory cytokine, is associated with both diseases and can serve as a common therapeutic target in CD. We report a rare case of coexisting unicentric Castleman disease in a young patient with Crohn's disease.