# Epidermodysplasia Verruciformis: A Case Series

## TL;DR

This paper presents three cases of a rare skin condition called epidermodysplasia verruciformis, highlighting its varied symptoms and cancer risks.

## Contribution

The study contributes by documenting diverse clinical presentations and management strategies in three EV cases.

## Key findings

- One patient developed squamous cell carcinoma in sun-exposed areas.
- Another patient showed a rare association with palmar pits.
- All patients were treated with oral retinoids and advised photoprotection.

## Abstract

Epidermodysplasia verruciformis (EV) is an uncommon disease that is inherited autosomal recessively. It has a heightened vulnerability to human papillomavirus (HPV) infection, which manifests as hyperpigmented or hypopigmented macular lesions, lesions resembling pityriasis versicolor (PV) and planar warts, and an increased risk of progressing to skin cancer, especially in sun-exposed areas. We report three cases of EV with varying presentations. One patient, a long-standing case of EV, developed squamous cell carcinoma (SCC) in the vulva and inguinal region. Another patient had a rare association with palmar pits, while the third patient presented with classical EV. All our patients were prescribed oral retinoids and advised to practice stringent photoprotection after histopathology confirmed evidence of EV.