# (Ir)reversibility of structural and functional brain alterations in severe anorexia

**Authors:** L.-K. Kaufmann

PMC · DOI: 10.1192/j.eurpsy.2024.36 · 2024-08-27

## TL;DR

This paper explores whether brain changes in severe anorexia can reverse with weight recovery, based on recent neuroimaging studies.

## Contribution

It highlights dynamic brain recovery processes during and after inpatient treatment for severe anorexia.

## Key findings

- Structural and functional brain changes are prominent during acute underweight in anorexia.
- Weight normalization may lead to partial reversal of these brain alterations.
- Recovery processes vary dynamically during and after treatment.

## Abstract

Anorexia nervosa is characterized by profound structural and functional brain alterations, particularly during the phase of acute underweight. Understanding the reversibility of these changes upon weight normalization is an important question in the pursuit of recovery and relapse prevention. This talk shares findings from recent neuroimaging studies, focussing on the dynamic processes of brain recovery observed during and after inpatient treatment in individuals with severe anorexia nervosa.

None Declared

## Linked entities

- **Diseases:** anorexia nervosa (MONDO:0005351)

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Source: https://tomesphere.com/paper/PMC11862712