The link between early life stress and psycho-cardio-metabolic multi-morbidity: Findings from The EarlyCause Consortium

TL;DR

This paper explores how early life stress affects mental and physical health outcomes later in life.

Contribution

The study provides new insights into how early life stress contributes to psycho-cardio-metabolic comorbidity.

Findings

Early life stress is linked to increased risk of psycho-cardio-metabolic comorbidity.

Prenatal and postnatal stress effects differ in their impact on health outcomes.

Moderating and mediating factors influence the relationship between stress and comorbidity.

Abstract

In this talk I will present new findings from EarlyCause, a European consortium which aims to better understand the link between early life stress and the development of psycho-cardiometabolic (PCM) comorbidity across the lifespan, leveraging data from large-scale pediatric and adult population studies. I will discuss findings regarding the effect of (prenatal and postnatal) early life stress on PCM health outcomes and their comorbidity, potential moderating and mediating factors, as well as evidence for causality.

None Declared