# Chronic Kidney Disease With Related Oral Health Problems and Alterations in the Tongue Microbiome Illustrated by a 15-Year-Old Girl: A Case Report

## TL;DR

A 15-year-old girl with chronic kidney disease shows oral health issues and a disrupted tongue microbiome, highlighting the need for intensive oral care in young CKD patients.

## Contribution

This case report provides insights into oral health management for young CKD patients through a detailed clinical example.

## Key findings

- The patient exhibited severe gingivitis and hyperplasia linked to CKD stage 4 and methylmalonic aciduria.
- Oral hygiene interventions and prophylaxis were necessary to manage oral health deterioration.
- Extended prophylaxis intervals worsened oral health, emphasizing the need for frequent care.

## Abstract

Chronic kidney disease (CKD) is characterised by a gradual loss of kidney function over time and is often linked to oral health issues. This case illustrates typical conditions in young CKD patients based on a 15-year-old girl with CKD stage 4 and methylmalonic aciduria, severe gingivitis and hyperplasia of the gingiva, and a need for orthodontic treatment. Oral hygiene interventions, homecare instructions and deep cleaning under antibiotic shielding were necessary to improve the patient's oral health. The immediate worsening of oral health status after extending the interval between regular prophylaxis appointments highlights the need for intensive prevention in young CKD patients to control oral health disorders. This report aims to demonstrate burden-of-care-reducing oral prophylaxis options for patients suffering from severe CKD with oral manifestations.

Trial Registration: German Registry of Clinical Trials: DRKS00010580