What Is the Significance of Placental Lakes in Pregnancy? A Historic Literature Review
Joanna Choi-Klier, Stephanie Masters, Danielle Lewis, Kaitlyn Taylor, Everett F. Magann

TL;DR
This review explores whether placental lakes seen in ultrasounds affect pregnancy outcomes and finds mixed evidence with some risks linked to large or multiple lakes.
Contribution
The paper provides a comprehensive review of placental lakes' potential impact on pregnancy outcomes, highlighting conflicting findings and risk factors.
Findings
Placental lakes are associated with risks like hypertensive disorders and fetal growth restriction in some studies.
Other studies found no adverse outcomes linked to placental lakes.
Larger or multiple lakes and thick placentas may increase the risk of adverse outcomes.
Abstract
Background/Objectives: The presence of placental lakes has been recognized on obstetric ultrasounds for many years, although their influence on pregnancy and perinatal outcomes remains uncertain. Most studies evaluating outcomes are small and many outcomes are conflicting. The question remains whether placental lakes affect pregnancy outcomes and, if so, how and under what circumstances? The purpose of this review was to determine the incidence, diagnosis, pathology, management, and pregnancy outcomes to determine the influence of an isolated lake versus the influence of a lake with the presence of other factors on pregnancy and perinatal outcomes. Methods: Electronic databases (PubMed, OVID, CINAHI, Embase, and Web of Science) were searched. The only limitation was the abstract/paper had to be in English. The search years were 1980–2023. The search terms included “placenta lake” AND…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsPregnancy and preeclampsia studies · Maternal and fetal healthcare · Birth, Development, and Health
