# Safety and Effectiveness of a Peripheral Rheolytic Thrombectomy Catheter in ST-Segment Elevation Myocardial Infarction: A Case Series

**Authors:** Giuseppe Giacchi, Agnese Bentivegna, Ida Logatto, Antonino Nicosia

PMC · DOI: 10.3390/jcdd12020072 · 2025-02-14

## TL;DR

A peripheral thrombectomy catheter was safely used in six patients with severe heart attacks, showing promise in reducing clot burden.

## Contribution

Demonstrates the potential use of a peripheral rheolytic thrombectomy catheter for treating high-thrombus coronary lesions in heart attack patients.

## Key findings

- The AngioJet Solent® Dista catheter effectively reduced thrombus burden in all six cases.
- Mid-term follow-up showed no angina recurrence and minimal in-hospital adverse events.
- One case of no-reflow occurred, but no major complications were observed.

## Abstract

Percutaneous treatment of highly thrombotic coronary lesions is demanding, due to worse acute and long-term clinical outcomes. In this report, we describe a case series of six patients with ST-segment elevation myocardial infarction and high-thrombus-burden coronary lesions. All patients were treated with the AngioJet Solent® Dista catheter, a rheolytic thrombectomy device designed for peripheral use. The catheter effectively reduced the thrombus burden in all cases, achieving satisfactory final angiographic results. One case of no-reflow was observed following lesion dilatation prior to thrombectomy, but no other major in-hospital adverse events occurred. At mid-term follow-up, all patients remained free from angina. These preliminary findings suggest that this approach could represent a promising option for managing highly thrombotic coronary lesions, but further studies with larger populations and long-term follow-up are needed to confirm these results.

## Linked entities

- **Diseases:** ST-segment elevation myocardial infarction (MONDO:0041656)

## Full-text entities

- **Diseases:** thrombus (MESH:D013927), thrombotic coronary lesions (MESH:D003328), coronary lesions (MESH:D003327), no-reflow (MESH:D054318), angina (MESH:D000787), ST-Segment Elevation Myocardial Infarction (MESH:D000072657)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11856912/full.md

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Source: https://tomesphere.com/paper/PMC11856912