# Pediatric and Juvenile Strabismus Surgery Under General Anesthesia: Functional Outcomes and Safety

**Authors:** Jakob Briem, Sandra Rezar-Dreindl, Lorenz Wassermann, Katharina Eibenberger, Franz Pusch, Ursula Schmidt-Erfurth, Eva Stifter

PMC · DOI: 10.3390/jcm14041076 · 2025-02-08

## TL;DR

This study shows that strabismus surgery under general anesthesia is safe for children and improves eye alignment and stereovision.

## Contribution

The study provides evidence on the safety and effectiveness of strabismus surgery in children across a wide age range.

## Key findings

- Strabismus surgery under general anesthesia is safe with low complication rates in children aged 0–18 years.
- Postoperative stereovision improved significantly, with over 80% of patients showing positive results.
- Intraoperative oculocardiac reflex occurred more frequently in children over 6 years old.

## Abstract

Background/Objectives: The aim of this paper was to evaluate the safety of surgical intervention using anesthesia and ophthalmological parameters in pediatric strabismus patients. The design involved retrospective case series. Methods: The setting was the Department of Ophthalmology, Medical University Vienna, Austria. Participants: In total, 208 children aged 0–18 years who underwent strabismus surgery due to exotropia or esotropia between 2013 and 2020 were included. Main outcomes and measures: Information regarding the duration of surgery, intra- and postoperative complications, the postoperative angle of deviation (AoD), and functional outcomes (visual acuity, stereovision) were analyzed. Results: The mean age at the time of surgery was 6.0 ± 4.1 years (range 0.6–18.0). The mean anesthesia time among all patients was 75.9 ± 19.3 min. The mean surgery and anesthesia time did not differ between the age groups. Longer anesthesia durations and surgery durations did not have a significant effect on the occurrence of intraoperation complications (p = 0.610 and p = 0.190, respectively). Intraoperative complications were recorded in 53% (most frequent triggering of oculocardiac reflex (OCR)) of the patients, and postoperative complications in 22% (the most frequent were postoperative nausea and vomiting and pain). An OCR was triggered more often in children older than 6 years than in younger children (p = 0.016). The mean angle of deviation was significantly reduced from preoperative to postoperative measurements. Preoperative stereovision tests were positive in 35% of the patients and increased to over 80% postoperatively. Conclusions: Strabismus surgery performed under general anesthesia in children aged 0 to 18 years is safe with regard to both surgical and anesthetic complications. A significant decrease in the angle of deviation and high rate of stereovision could be achieved with a low rate of re-treatments. However, the retrospective design, absence of standardized documentation, and limited sample size may affect the consistency and comparability of this study’s findings.

## Linked entities

- **Diseases:** strabismus (MONDO:0003432), exotropia (MONDO:0001286), esotropia (MONDO:0004896)

## Full-text entities

- **Diseases:** pain (MESH:D010146), esotropia (MESH:D004948), exotropia (MESH:D005099), Strabismus (MESH:D013285), postoperative complications (MESH:D011183), postoperative nausea and vomiting (MESH:D020250)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC11856483