# Poor sleep patterns are associated with the prevalence of benign prostatic hyperplasia in US aged 40 and older: A cross-sectional study based on NHANES

## TL;DR

Poor sleep patterns in men over 40 in the U.S. are linked to a higher risk of benign prostatic hyperplasia (BPH).

## Contribution

This study is the first to show a significant association between sleep patterns and BPH in U.S. men aged 40 and older.

## Key findings

- Short sleep duration (less than 7–9 hours) is associated with a 92% higher risk of BPH.
- Trouble sleeping and sleep disorders are strongly linked to BPH.
- Men with poor sleep patterns have a 107% higher risk of BPH.

## Abstract

The connection between sleep patterns (sleep duration, trouble sleeping and sleep disorders) and benign prostatic hyperplasia, commonly referred to as BPH, is not yet clear. Our aim is to investigate the impact of sleep patterns on BPH risk in US men aged 40 and older.

We performed an observational analysis using data from NHANES 2005–2008 on males aged 40 and up, including a total of 2,555 participants. After accounting for confounding variables, we applied weighted multivariable logistic regression to assess the relationship between sleep patterns and BPH risk according to the complex multi-stage sampling design of NHANES.

In this study, 11.79% of the 2,555 American participants aged over 40 reported to have BPH. after adjusting for confounding variables, multivariable logistic regression analysis showed that short sleep duration, compared to healthy sleep duration (7–9 hours), was linked to a significantly higher risk of BPH (OR: 1.92, 95% CI: 1.42–2.41). Trouble sleeping and sleep disorder were also strongly associated with BPH. Moreover, there appears to be a stronger association among those with poor sleep patterns (OR: 2.07, 95% CI: 1.46–2.91).

Poor sleep patterns in men over 40 in the U.S. is significantly linked to a higher incidence of benign prostatic hyperplasia.